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at the level of each integration project, between applications that are selected according to departmental needs. Some recommendations can be made: deploying a version of the integration infrastructure involves much more than just taking account of the constraints of projects that will use it; the frequency of infrastructure versions must be lower than the frequency of project implementations; it is important to look for incremental edges between successive versions, so as not to put the whole of a previous version in question, and thus require a complete re-test; at the same time the application integration solution is launched, a capitalization program must be put in place; this capitalization program is input from development activities carried out during projects, by determining what will be useful in subsequent projects; the project launch phase can involve generic aspects that have already been capitalized on; the project assessment phase can involve looking for developments that could be capitalized; the project initialization phase must immediately define objectives, quantifying the means to establish scheduling; an application integration competency center is recommended at the same time as the initialization phase; the generic (capitalizable) aspects most often encountered include: - technical or business connectors; - access to enterprise repositories to check the dataflows; - definitions of pivot formats; - industrialization of parameter settings for transformations; - solution integration tests; - audit trails and supervision of the dataflows; - best practice recommendations for integration components; - frequently asked questions ( FAQ ).

Is it interesting Is it believable Does it fit with what they are doing today Does it play to their strengths Have they delivered on their promises reliably in the past What is the company vision Is it realistic Cross-platform support Can the same product be delivered on all, or most, of your critical computing platforms How similar are the products on different platforms Can the different platform products be administered easily and centrally If products are similar between different platforms, system administrative costs can be reduced significantly, as less training must be purchased to teach sys admins how to operate the products, and to keep them up-to-date later on In many cases, if products are similar enough between operating systems, fewer administrators may be required, saving even more money.

where k is the decomposition rate constant for the enzyme substrate complex (either k2 or kcat), Et is the total number of moles of enzyme immobilized, and the value of b is a constant for a given reactor, and is equal to the ratio of reactor void volume to total reactor volume (i.e., b is always less then unity). The degree of reaction, P, varies between zero (no product formed) and unity (complete conversion of substrate). An equation equivalent to the Michaelis Menten equation has been derived for immobilized enzymes in packed-bed reactor systems, and is given in Eq. 4.24:

Even if you are running a singleplatform shop, remember that that state of affairs can change overnight through a merger, acquisition, or change in CIO It s best to be prepared Stick with your vendors After you have chosen vendors you are happy with, try to stay with them You should still evaluate products from other vendors, but once vendors are in and you are happy with their treatment, they should be treated as incumbents; don t kick them out unless the competition is clearly superior If you show your vendors loyalty, they will show loyalty back to you, often with superior pricing, support, and perks..

11

4:24

Limit the number of vendors. It is much easier to work with 3 or 4 vendors than it is to work with 20. You ll have to deal with less intervendor dissent and competition, and you ll spend less of your time in sales presentation meetings. However, if you limit your number of vendors down to just one, that vendor can represent a single point of failure. If you ve put all your eggs in a single basket, and something does happen to that basket, you can be in a lot of trouble. Three or four vendors is probably the right number.

where Q is the volume ow rate of the mobile phase. In general, this equation predicts that for a given column capacity, the degree of reaction, P, is inversely related to the mobile-phase ow rate, Q. That is, the faster the analyte plug ows through the reactor, the less likely will be its complete conversion into product. Equation 4.24 has been experimentally tested using a carboxymethylcellulose stationary phase onto which the enzyme cin (E.C.3.4.22.3) has been immobilized. Ficin catalyzes the hydrolysis of a variety of ester substrates, but the substrate Nbenzoyl-L-arginine ethyl ester (BAEE) has been chosen for this series of experiments (Eq. 4.25):