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How to start and stop an application What to do when a failover occurs What to do when systems fail completely What to do when a site disaster occurs What to do when the data center power will be shut down for a weekend Servers Clients Applications Monitoring tools Physical data center changes

Notation linked to the SLA The notation grid for the service level agreement could show the following.

11

The antigen-binding site of an antibody has a structure that allows a complementary t with structural elements and functional groups on the antigen The portion of the antigen that interacts speci cally with the antigen-binding site on the antibody is called the antigenic determinant, or epitope The epitope has a size of $ 0:7 1:2 3:5 nm, which is equivalent to $ 5 7 amino acid residues The complementary site on the antibody is called the paratope, and this has about the same size Antigens may be classi ed according to their binding characteristics of valency (meaning the total number of sites) and their determinacy (meaning the number of different types of sites)5 There are four classes of antigens: 1 Only a single epitope on the surface that is capable of binding to an antibody: unideterminate and univalent Haptens are unideterminate and univalent 2.

Network layout Hardware diagrams for every critical system A diary of all system and network outages, planned and unplanned, including the cause and the amount of downtime incurred

Two or more epitopes of the same kind on one antigen molecule: unideterminate and multivalent 3 Many epitopes of different kinds, but only one of each kind on one antigen molecule: multideterminate and univalent Most protein antigens fall into this category 4 Many epitopes of different kinds, and more than one of each kind per antigen molecule: multideterminate and multivalent Proteins containing multiple identical subunits, as well as polymerized proteins and whole cells, fall into this category..

Start with that list, and see where it goes. Documentation should contain many cross-references to external documentation and to other parts of internal documentation so that you don t write the same information in more than one place. If someone else has written it down, use that person s copy. If different parts of the same documents disagree, which is inevitable over time without great care, a tremendous amount of time can be wasted trying to determine which passage is correct. Documentation should always be marked with a date and version number, with both updated whenever the slightest change is made. There should even be a manual about the documentation itself. This manual should contain standards information for new and existing documentation things like distribution models, update procedures, version numbering standards, formatting, storage standards, and so on. And all system documentation should include update the documentation as one of the steps to perform when a documented component is changed or added. All the while, be sure that you keep things as simple as possible (always remember Key Principle #1!). People will have to read the documentation that you ve written. If it is unreadable, or unusable, then there is no point to having it at all, and you ll have wasted a tremendous amount of your own time and created a great deal of frustration among your audience.

When you sit down to write anything (a book, a magazine article, a school essay, a diary entry, a love letter or anything else), the first question you must ask yourself is who the audience is for the document. In the case of system documentation, as mentioned in 5, some experts will say that it must be written at a very low and simple level so that anyone, from the janitor (or the CEO, as some wags will tell you) to the head of systems, could pick it up and recover a system from whatever ill may have befallen it. That is a surefire recipe for failure. Documentation cannot possibly be written so that a total novice could recover a system from any outage. There are far too many variables and options