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Stewart Brand s book is a wonderful resource for all architects, whether you re working with silicon, steel, or sofas. The preceding quote captures the tension between those who design structures, like availability platforms, and those who make things happen within them, namely those who design the applications that run on those platforms. We ve been describing availability building blocks in series of more complex layers, starting with a foundation of data management and working up through network redundancy. Applications fit in at Level 7 of the Availability Index because they need to be well conditioned before you think about clustering them or adding other external recovery mechanisms around them. Systems and applications compose an application platform; that is, they are the pieces you use to support an application that actually does something interesting. Unless you run benchmarks for a living, you probably don t just run a database; you run an application that talks to the database.

While no real labels meet all of these needs, the properties of some of the more recently introduced labelling systems are approaching the ideal. Radioisotopes, once the only type of label used for immunoassays, have clearly been overwhelmed by current applications of uorescent labeling methods, enzyme labels, and even coenzyme and prosthetic group labels. A variety of alternative labels has also been investigated, including red blood cells, latex particles, viruses, metals, and free radicals. Table 6.1 shows a representative listing of labels used in modern immunoassays.1

13

Services and Applications Client Management Local Environment Networking Disk and Volume Management Reliable Backups Good System Administration Practices INVESTMENT

Network services authorize: support for different types of networks (TCP/IP, X.25, SNA, DSA, DNA, etc.); commutation of networks (example: TCP/IP to X.25); capacity to initiate a connection (requester), or wait for the connection from another manager (server), as required. File transfer protocol services allow: support for different file exchange protocols (PeSIT and ETEBAC in banking, OFTP in automotive, FTAM, etc.);

Immunoassay Type Heterogeneous Label Type Fluorophore Label Fluorescein Europium chelate Phycobiliproteins Acridinium ester Phenanthridinium ester Alkaline phosphatase b-Galactosidase Peroxidase Urease ATP NAD Mellitin Property Measured Fluorescence intensity Time-resolved uorescence Fluorescence intensity Ester hydrolysis Ester hydrolysis Enzyme activity Enzyme activity Enzyme activity Enzyme activity Kinase activity Dehydrogenase activity Release of liposometrapped enzyme (activity) Binds avidin-enzyme and streptavidin-enzyme conjugates (activity) Fluorescence polarization Fluorescence quenching Fluorescent energy transfer Ester hydrolysis Light emission Glucose oxidase activity

There are two aspects to application recovery: First, how does the application react when a data service fails, and second, what else might go wrong within the application code that would cause a failure Sometimes it s the application to blame, dumping core or behaving erratically when the network and all of its services are just fine. In this chapter, we add to our analysis of design rules and building blocks with an investigation of application-level recovery, starting with a list of failure modes and application reactions, then we take a brief look at internal application failures, some process-level replication techniques. We conclude with an overview of good developer habits that improve overall system reliability.

Service availability only ensures that a data management service like a database is at the ready on the network. In the previous chapter, we looked at what might happen to client systems that don t tolerate failures well. On the server side, your user-level applications may not be able to access these data management services if they are not configured to deal with redundancy and get confused after a server failover. Applications may not deal with failures in a gentle manner, resulting in application crashes or endless streams of errors while they try to recover or reconnect to the wrong server. Application-level reliability is a trap for finger-pointing: The front-end team blames the backend team for making their part of the application crash; the web designers insist they didn t do anything on the edge that would make a browser seize up; the database team blames the middleware selection for failing to route

Acridinium ester Isoluminol FAD Glucose-6-phosphate dehydrogenase Malate dehydrogenase Peroxidase Hexokinase Ferrocenes Nitroxides Galactosyl-umbelliferone

transactions after a failover, while the middleware team insists it s a database recovery problem. Developing good detection and prevention techniques will help you sort through these situations.